Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia

Author:

Tothova Zuzana,Krill-Burger John M.,Popova Katerina D.,Landers Catherine C.,Sievers Quinlan L.,Yudovich David,Belizaire Roger,Aster Jon C.,Morgan Elizabeth A.,Tsherniak Aviad,Ebert Benjamin L.

Funder

NIH

Edward P. Evans Foundation

Gabrielle's Angel Foundation

LLS Scholar Award

Broad Ignite

Broad Institute of MIT and Harvard

LLS Special Fellow Award

ASCO Young Investigator Award

ASH/EHA Translational Research in Hematology Award

NIDDK

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference31 articles.

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3. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamini;J. R. Stat. Soc. Series B Stat. Methodol.,1995

4. MLL leukemia induction by genome editing of human CD34+ hematopoietic cells;Buechele;Blood,2015

5. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission;Corces-Zimmerman;Proc. Natl. Acad. Sci. USA,2014

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