Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation

Author:

Thomas Charles A.,Tejwani Leon,Trujillo Cleber A.,Negraes Priscilla D.,Herai Roberto H.,Mesci Pinar,Macia Angela,Crow Yanick J.,Muotri Alysson R.

Funder

NIH

Ruth L. Kirschstein NRSA Fellowship

California Institute for Regenerative Medicine (CIRM)

UCSD CTRI

NARSAD

European Research Council

ERA-NET Neuron

National Research Agency

Roche Postdoc Fellowship Program

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference70 articles.

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3. Modified Hirt procedure for rapid purification of extrachromosomal DNA from mammalian cells;Arad;Biotechniques,1998

4. Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis;Bloom;JAMA Neurol.,2014

5. Evidence consistent with human L1 retrotransposition in maternal meiosis I;Brouha;Am. J. Hum. Genet.,2002

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