Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex

Author:

Han Min,Lv Qing,Tang Xin-Jiang,Hu Yu-Lan,Xu Dong-Hang,Li Fan-Zhu,Liang Wen-Quan,Gao Jian-Qing

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference24 articles.

1. Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line;Meng;ACS Nano,2010

2. Recent attempts at RNAi-mediated P-glycoprotein downregulation for reversal of multidrug resistance in cancer;Abbasi;Med. Res. Rev.,2011

3. Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells;Diao;Int. J. Nanomedicine,2011

4. Molecular mechanism study of chemosensitization of doxorubicin-resistant human myelogenous leukemia cells induced by a composite polymer micelle;Han;Int. J. Pharm.,2011

5. Clinical development of P glycoprotein modulators in oncology;Oza;Novartis Found. Symp.,2002

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