UPLC-MS/MS analysis of CYP1A-mediated ethoxyresorufin-O-deethylation activity in the rat kidney microsomes

Author:

Venkatapura Chandrashekar Devaraj,Mehvar Reza

Funder

Chapman University School of Pharmacy

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference23 articles.

1. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol. Ther.,2013

2. Renal drug metabolism;Lohr;Pharmacol. Rev.,1998

3. Dose-dependent up-regulation of rat pulmonary, renal, and hepatic cytochrome P-450 (CYP) 1A expression by nicotine feeding;Iba;Drug Metab. Dispos.,1999

4. The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals;Ioannides;Drug Metab. Rev.,1990

5. Characterization of arachidonic acid metabolism by rat cytochrome P450 enzymes: the involvement of CYP1As;El-Sherbeni;Drug Metab. Dispos.,2014

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