Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin-Reference-Cited by-同舟云学术

Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin

Published:2010-11-01 Issue:11 Volume:59 Page:1383-1386
ISSN:0022-2615
Container-title:Journal of Medical Microbiology
language:en
Short-container-title:

Author:

Humphries Romney M.¹,Kelesidis Theodoros²,Dien Bard Jennifer¹,Ward Kevin W.³,Bhattacharya Debika²,Lewinski Michael A.¹

Affiliation:

1. UCLA David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, Los Angeles, CA, USA

2. Department of Medicine, Division of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

3. UCLA Medical Center, Los Angeles, CA, USA

Abstract

The spread of antimicrobial resistance among members of the Enterobacteriaceae is a significant clinical threat. We report the treatment of pan-resistant Klebsiella pneumoniae bacteraemia with combination tigecycline and colistin in a 49-year-old male and review available therapeutic options. Despite a poor prognosis, the patient recovered, but remains colonized with the pan-resistant isolate.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

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