Non-O1, non-O139 Vibrio cholerae bacteraemia in a cirrhotic patient

Author:

Petsaris O.12,Nousbaum J. B.3,Quilici M. L.4,Le Coadou G.3,Payan C.12,Abalain M. L.12

Affiliation:

1. Faculté de Médecine et des Sciences de la Santé, Université de Brest, EA 3882, 29200 Brest, France

2. Laboratoire de Microbiologie, Centre Hospitalier Universitaire La Cavale Blanche, Boulevard Tanguy Prigent, 29609 Brest cedex, France

3. Service d'Hépato-Gastroentérologie, Centre Hospitalier Universitaire la Cavale Blanche, 29609 Brest cedex, France

4. Centre National de Référence des Vibrions et du Choléra, Institut Pasteur, 75724 Paris cedex 15, France

Abstract

Vibrio cholerae serogroups O1 or O139 are the aetiological agents of cholera. The pathogenicity of non-O1, non-O139 V. cholerae is less well known. These worldwide bacteria are responsible for gastrointestinal infections or, more rarely, bacteraemia in patients with an underlying disease, leading to life-threatening complications. We report a case of non-O1, non-O139 V. cholerae bacteraemia due to a haemolytic strain in a cirrhotic patient. Early antibiotherapy allowed a good outcome. The aim of this case report is to underline the virulence of non-choleragenic Vibrio strains, possibly linked to haemolysin production, and the potential danger of consuming undercooked seafood or exposing wounds to sea water in cirrhotic patients.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

Reference17 articles.

1. Non-O1 Vibrio cholerae septicemia: case report, discussion of literature, and relevance to bioterrorism;Anderson;Diagn Microbiol Infect Dis,2004

2. Non-O1, non-O139 Vibrio cholerae bacteraemia in splenectomised thalassaemic patient from Malaysia;Deris;Trop Biomed,2009

3. Vibrio cholerae (non-O1, non-O139) sepsis in a child with Fanconi anemia;Dhar;Diagn Microbiol Infect Dis,2004

4. Septicaemia and liver abscesses secondary to non-O1/non-O139 Vibrio cholerae colitis;Farmachidi;Eur J Gastroenterol Hepatol,2003

5. The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model;Fullner;J Exp Med,2002

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