Prevalence of SARS-CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India-Reference-Cited by-同舟云学术

Prevalence of SARS-CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India

Published:2024-06-01 Issue:6 Volume:6 Page:
ISSN:2516-8290
Container-title:Access Microbiology
language:en
Short-container-title:

Author:

Meghna Nupur¹^ORCID,Archana Archana¹^ORCID,Bhushan Divendu²^ORCID,Kumar Abhyuday³^ORCID,Sarfraz Asim¹^ORCID,Naik Bijaya Nanda⁴^ORCID,Pati Binod Kumar¹^ORCID

Affiliation:

1. Department of Microbiology, All India Institute of Medical Sciences, Patna, India

2. Department of General Medicine, All India Institute of Medical Sciences, Patna, India

3. Department of Anaesthesiology, All India Institute of Medical Sciences, Patna, India

4. Department of Community and Family Medicine, All India Institute of Medical Sciences, Patna, India

Abstract

Introduction. The coronavirus illness caused by SARS-CoV-2 can cause multiple organ involvement, with varying degrees of severity. Besides inhalation as a route for transmission, feco-oral has also been proposed. Its transmission to sewage systems is a growing public health issue. Objective. To detect SARS-CoV-2 RNA in non-respiratory samples (saliva, urine, and stool) collected from COVID-19 cases, in Bihar. Methods. This cross-sectional observational study was conducted from January 2021 to March 2022 on human non-respiratory samples. A total of 345 samples including saliva (116), stool (97), and urine (132) were collected from 143 COVID-19 cases. Samples were analysed for SARS-CoV-2 by multiplex RT-PCR targeted against E, ORF 1ab, and RdRp genes. Results. In this study, out of 143 cases, a total of 107 (74.8 %) were positive for SARS-CoV-2 RNA in at least one of the non-respiratory samples. Conclusion. There is a high prevalence of SARS-CoV-2 virus in non-respiratory samples.

Publisher

Microbiology Society

Link

https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000693.v4?crawler=true&mimetype=application/pdf

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