Spread of community-acquired meticillin-resistant Staphylococcusaureus skin and soft-tissue infection within a family: implications forantibiotic therapy and prevention

Author:

Amir N. H.1,Rossney A. S.2,Veale J.3,O'Connor M.1,Fitzpatrick F.41,Humphreys H.51

Affiliation:

1. Department of Clinical Microbiology, Beaumont Hospital,PO Box 1297, Beaumont Road, Dublin 8, Ireland

2. National MRSA Reference Laboratory, St James'sHospital, James's Street, Dublin 8, Ireland

3. Temenos Medical Centre, Malahide, Dublin, Ireland

4. Health Protection Surveillance Centre, 25–27Middle Gardiner Street, Dublin 1, Ireland

5. Department of Clinical Microbiology, RCSI Educationand Research Centre, Smurfit Building, Beaumont Hospital, PO Box 9063, Dublin9, Ireland

Abstract

Outbreaks or clusters of community-acquired meticillin-resistant Staphylococcusaureus (CA-MRSA) within families have been reported. We describea family cluster of CA-MRSA skin and soft-tissue infection where CA-MRSA wassuspected because of recurrent infections which failed to respond to flucloxacillin.While the prevalence of CA-MRSA is low worldwide, CA-MRSA should be consideredin certain circumstances depending on clinical presentation and risk assessment.Surveillance cultures of family contacts of patients with MRSA should be consideredto help establish the prevalence of CA-MRSA and to inform the optimal choiceof empiric antibiotic treatment.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

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