ICTV Virus Taxonomy Profile: Coronaviridae 2023

Author:

Woo Patrick C. Y.1,de Groot Raoul J.2,Haagmans Bart3,Lau Susanna K. P.4,Neuman Benjamin W.5,Perlman Stanley6,Sola Isabel7,van der Hoek Lia8,Wong Antonio C. P.4,Yeh Shiou-Hwei9

Affiliation:

1. PhD Program in Translational Medicine and Department of Life Sciences, National Chung Hsing University, Taichung 402, Taiwan, ROC

2. Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands

3. Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands

4. Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, PR China

5. Department of Biology, Texas A&M University, College Station, Texas, 77843, USA

6. Departments of Microbiology and Immunology, and Pediatrics, University of Iowa, Iowa City, IA 52242, USA

7. Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish, National Research Council (CNB-CSIC), Madrid, Spain

8. Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, Laboratory of Experimental Virology, Location University of Amsterdam, 1105 AZ Amsterdam, Netherlands

9. Department of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC

Abstract

The family Coronaviridae includes viruses with positive-sense RNA genomes of 22–36 kb that are expressed through a nested set of 3′ co-terminal subgenomic mRNAs. Members of the subfamily Orthocoronavirinae are characterized by 80–160 nm diameter, enveloped virions with spike projections. The orthocoronaviruses, severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome-related coronavirus are extremely pathogenic for humans and in the last two decades have been responsible for the SARS and MERS epidemics. Another orthocoronavirus, severe acute respiratory syndrome coronavirus 2, was responsible for the recent global COVID-19 pandemic. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Coronaviridae which is available at www.ictv.global/report/coronaviridae.

Publisher

Microbiology Society

Subject

Virology

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