Author:
Nath Dipankar,Chetia Dipak
Abstract
Metabolomics utilizes analytical profiling technique for measuring and comparing large numbers of metabolites produced in the biological fluids. Traditional process of drug development is not sufficient enough to understand the proper biochemical processes within the targets which may finally lead to the failure. Metabolomics can be very useful to overcome such failure as it involves in the detailed profiling and understanding of the biochemical processes which helps in identification of target engagement (TE) markers as well as predicting mode of action (MOA). Currently pharmaceutical companies are utilizing this approach in the early drug development stage to combat failure. This chapter will mainly highlight the advantages of this concept over traditional concept of drug development along with recent developments of it.
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