Modern View on Very Early Onset and Early Onset Inflammatory Bowel Diseases in Children-Reference-Cited by-同舟云学术

Modern View on Very Early Onset and Early Onset Inflammatory Bowel Diseases in Children

Published:2024-07-12 Issue:3 Volume:23 Page:145-151
ISSN:1682-5535
Container-title:Current Pediatrics
language:
Short-container-title:Vopr. sovr. pediatr.

Author:

Khavkin Anatoly I.¹^ORCID,Permyakova Anastasiya A.²^ORCID,Tsepilova Mariya O.²^ORCID,Kaplina Aleksandra V.³^ORCID,Sitkin Stanislav I.⁴^ORCID,Surkov Andrey N.⁵^ORCID,Getmanov Stanislav D.⁶^ORCID

Affiliation:

1. Research and Clinical Institute for Children; Belgorod State University

2. Saint Petersburg State Pediatric Medical University

3. Almazov National Medical Research Centre

4. Almazov National Medical Research Centre; North-Western State Medical University named after I.I. Mechnikov

5. Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University

6. Pirogov Russian National Research Medical University

Abstract

Nowadays, an urgent problem of pediatric gastroenterology is the study of inflammatory bowel diseases with very early onset (VEO-IBD), which have unique genetic, clinical, immunological, morphological, and laboratory sings. Early VEO-IBD is usually considered as monogenic disease, especially in combination with congenital immune defects, which leads to difficulties in diagnosis and management this pathology. Despite this, systematization of information about this group of nosological forms of IBD is practically not carried out. This article presents a review of the available information on etiological factors, course variants, and therapeutic options for VEO-IBD.

Publisher

Paediatrician Publishers LLC

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