The Genetic Diversity of the Americas

Author:

Adhikari Kaustubh1,Chacón-Duque Juan Camilo1,Mendoza-Revilla Javier12,Fuentes-Guajardo Macarena13,Ruiz-Linares Andrés145

Affiliation:

1. Department of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom

2. Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima 31, Perú

3. Departamento de Tecnología Médica, Facultad de Ciencias de la Salud, Universidad de Tarapacá, Arica 1000009, Chile

4. Ministry of Education Key Laboratory of Contemporary Anthropology and Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200438, China;

5. Laboratory of Biocultural Anthropology, Law, Ethics, and Health (Centre National de la Recherche Scientifique and Etablissement Français du Sang, UMR-7268), Aix-Marseille University, 13824 Marseille, France

Abstract

The history of the Americas involved the encounter of millions of Native Americans, Europeans, and Africans. A variable admixture of these three continental groups has taken place throughout the continent, influenced by demography and a range of social factors. This variable admixture has had a major influence on the genetic makeup of populations across the continent. Here, we summarize the demographic history of the region, highlight some social factors that affected historical admixture, and review major patterns of ancestry across the Western Hemisphere based on genetic data.

Publisher

Annual Reviews

Subject

Genetics(clinical),Genetics,Molecular Biology

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