Nano/Micro and Spectroscopic Approaches to Food Pathogen Detection

Author:

Cho Il-Hoon12,Radadia Adarsh D.3,Farrokhzad Khashayar4,Ximenes Eduardo25,Bae Euiwon6,Singh Atul K.7,Oliver Haley7,Ladisch Michael25,Bhunia Arun7,Applegate Bruce47,Mauer Lisa7,Bashir Rashid8,Irudayaraj Joseph12

Affiliation:

1. Bindley Bioscience and Birck Nanotechnology Center; Departments of

2. Agricultural and Biological Engineering,

3. Institute for Micromanufacturing, Biomedical Engineering Center, Louisiana Tech University, Ruston, Louisiana 71272

4. Biological Sciences,

5. Laboratory of Renewable Resources Engineering, Purdue University, West Lafayette, Indiana 47907;

6. Mechanical Engineering; and

7. Food Science, and

8. Department of Electrical and Computer Engineering, University of Illinois, Urbana-Champaign, Urbana, Illinois 61801

Abstract

Despite continuing research efforts, timely and simple pathogen detection with a high degree of sensitivity and specificity remains an elusive goal. Given the recent explosion of sensor technologies, significant strides have been made in addressing the various nuances of this important global challenge that affects not only the food industry but also human health. In this review, we provide a summary of the various ongoing efforts in pathogen detection and sample preparation in areas related to Fourier transform infrared and Raman spectroscopy, light scattering, phage display, micro/nanodevices, and nanoparticle biosensors. We also discuss the advantages and potential limitations of the detection methods and suggest next steps for further consideration.

Publisher

Annual Reviews

Subject

Analytical Chemistry

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