The Development and Application of Optogenetics-Reference-Cited by-同舟云学术

The Development and Application of Optogenetics

Published:2011-07-21 Issue:1 Volume:34 Page:389-412
ISSN:0147-006X
Container-title:Annual Review of Neuroscience
language:en
Short-container-title:Annu. Rev. Neurosci.

Author:

Fenno Lief¹²,Yizhar Ofer¹,Deisseroth Karl¹³⁴

Affiliation:

1. Department of Bioengineering, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305;

2. Department of Bioengineering, Neuroscience Program, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305;

3. Departments of Psychiatry and Behavioral Sciences, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305;

4. Departments of Psychiatry, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305;

Abstract

Genetically encoded, single-component optogenetic tools have made a significant impact on neuroscience, enabling specific modulation of selected cells within complex neural tissues. As the optogenetic toolbox contents grow and diversify, the opportunities for neuroscience continue to grow. In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms.

Publisher

Annual Reviews

Subject

General Neuroscience

Link

https://www.annualreviews.org/doi/pdf/10.1146/annurev-neuro-061010-113817

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