Functional Efficacy of Tendon Repair Processes

Author:

Butler David L.1,Juncosa Natalia1,Dressler Matthew R.1

Affiliation:

1. Department of Biomedical Engineering, Noyes-Giannestras Biomechanics Laboratory, University of Cincinnati, Cincinnati, Ohio 45221-0048;, ,

Abstract

▪ Abstract  Despite various attempts to repair and replace injured tendon, an understanding of the repair processes and a systematic approach to achieving functional efficacy remain elusive. In this review the epidemiology of tendon injury and repair is first examined. Using a traditional paradigm for repair assessment, the biology and biomechanics of normal tendon, natural healing, and repair are then explored. New treatment strategies such as functional tissue engineering are discussed, including a functional approach to treatment that involves the development of in vivo functional design parameters to judge the acceptability of a repair outcome. The paper concludes with future directions.

Publisher

Annual Reviews

Subject

Biomedical Engineering,Medicine (miscellaneous)

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