Engineering Flows in Small Devices: Microfluidics Toward a Lab-on-a-Chip

Author:

Stone H.A.1,Stroock A.D.2,Ajdari A.3

Affiliation:

1. Division of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138;

2. School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 14853;

3. Physico-Chimie Théorique, UMR CNRS-ESPCI 7083, ESPCI, 10 rue Vauquelin, 75005 Paris, France;

Abstract

Microfluidic devices for manipulating fluids are widespread and finding uses in many scientific and industrial contexts. Their design often requires unusual geometries and the interplay of multiple physical effects such as pressure gradients, electrokinetics, and capillarity. These circumstances lead to interesting variants of well-studied fluid dynamical problems and some new fluid responses. We provide an overview of flows in microdevices with focus on electrokinetics, mixing and dispersion, and multiphase flows. We highlight topics important for the description of the fluid dynamics: driving forces, geometry, and the chemical characteristics of surfaces.

Publisher

Annual Reviews

Subject

Condensed Matter Physics

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