EVALUATING THE COST-EFFECTIVENESS OF CLINICAL AND PUBLIC HEALTH MEASURES

Author:

Graham John D.12,Corso Phaedra S.12,Morris Jill M.12,Segui-Gomez Maria12,Weinstein Milton C.12

Affiliation:

1. Harvard Center for Risk Analysis, Harvard School of Public Health, 718 Huntington Avenue, Boston, Massachusetts 02115-5924;

2. Prevention Effectiveness Branch, Division of Prevention Research and Analytic Methods, Centers for Disease Control and Prevention, Atlanta, Georgia 30333;

Abstract

▪ Abstract  Cost-effectiveness analysis, an analytic tool that expresses as a ratio the cost of obtaining an additional unit of health outcome, can help decision makers achieve more health protection for the same or less cost. We characterize the state of the cost-effectiveness analysis literature by reviewing how this technique is applied to various clinical and public health interventions. We describe the results of cost-effectiveness analyses for over 40 interventions to reduce cancer, heart disease, trauma, and infectious disease. The cost-effectiveness ratios for these interventions vary enormously, from interventions that save money to those that cost more than $1 million per year of life gained. The methods used to derive the cost-effectiveness ratios also vary considerably, and we summarize this variation within each health area. Greater uniformity of analytical practice will be necessary if cost-effectiveness analysis is to become a more influential tool in debates about resource allocation.

Publisher

Annual Reviews

Subject

Public Health, Environmental and Occupational Health,General Medicine

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