Airway Smooth Muscle in Asthma-Reference-Cited by-同舟云学术

Airway Smooth Muscle in Asthma

Published:2008-02-01 Issue:1 Volume:3 Page:523-555
ISSN:1553-4006
Container-title:Annual Review of Pathology: Mechanisms of Disease
language:en
Short-container-title:Annu. Rev. Pathol. Mech. Dis.

Author:

Hershenson Marc B.¹,Brown Melanie²,Camoretti-Mercado Blanca³,Solway Julian³

Affiliation:

1. Departments of Pediatrics and Communicable Diseases, Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan 48109;

2. Departments of Pediatrics, University of Chicago, Chicago, Illinois 60637;

3. Departments of Medicine, University of Chicago, Chicago, Illinois 60637;,

Abstract

Airway smooth muscle plays a multifaceted role in the pathogenesis of asthma. We review the current understanding of the contribution of airway myocytes to airway inflammation, airway wall remodeling, and airflow obstruction in this prevalent disease syndrome. Together, these roles make airway smooth muscle an attractive target for asthma therapy.

Publisher

Annual Reviews

Subject

Pathology and Forensic Medicine

Link

https://www.annualreviews.org/doi/pdf/10.1146/annurev.pathmechdis.1.110304.100213

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