Can HCG MoM Ratio Predict Preeclampsia?

Author:

TOKGÖZ Betül1ORCID,KIZILBOĞA Gizem1ORCID,YILMAZ ERGANİ Seval1ORCID,KINDAN Aykut1ORCID,OBUT Mehmet1ORCID,DERELİ Levent1ORCID,YAKUT YÜCEL Kadriye1ORCID,SAĞLAM Erkan1ORCID,FIRATLIGİL Fahri Burçin1ORCID,ÖZKAN Sadullah1ORCID,KAYA Onur1ORCID,ÇAKIR Caner2ORCID,ÇELEN Şevki1ORCID,ÇAĞLAR Ali1ORCID,USTUN Yaprak1ORCID

Affiliation:

1. SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ

2. UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES

Abstract

Objective: To predict preeclampsia by the ratio of the HCG MoM value in the first and second trimester screening tests. Material and Methods: The HCG-MoM values of 136 pregnant women with preeclampsia and 222 normatensive pregnant women used for first and second-trimester screening tests were proportioned , and the difference between the groups was examined. Numeric variables are expressed as mean ± standard deviation, median (minimum – maximum), and categorical variables as n (%). Results: HCG MoM values were not different between the two groups and were within the accepted international values. The ratio of the free HCG MoM value in the first trimester to the intact HCG MoM value in the second trimester was significantly higher in the control group (1.06) than in the study group (0.99) (p=0.02). Conclusion: Rating the MoM values of β-HCG, a biochemical marker used in screening tests for chromosomal anomaly, may predict preeclampsia in the later weeks of pregnancy.

Publisher

Hitit University

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