Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection-Reference-Cited by-同舟云学术

Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection

Published:2024-01-24 Issue:4 Volume:22 Page:164-173
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Bespalova I. D.¹^ORCID,Mitrichenko U. M.¹^ORCID,Kalyuzhin V. V.¹^ORCID,Koroleva E. S.¹^ORCID,Koshchavtseva Yu. I.¹^ORCID,Romanov D. S.¹^ORCID,Pershina D. E.¹^ORCID

Affiliation:

1. Siberian State Medical University

Abstract

The review summarizes and analyzes the results of major foreign studies on the role of adipokine imbalance in the development of a severe course and complications of novel coronavirus infection (COVID-19). Adipokines are biologically active compounds produced by adipose tissue cells and involved in the regulation of metabolism and the functioning of the immune system. Obesity is a proven risk factor for severe COVID-19 due to high hormonal and metabolic activity of visceral adipose tissue. A deep understanding of COVID-19 pathogenesis from the point of view of the role of adipokine imbalance in it can provide the grounds for the development of effective pathogenetic approaches to the prevention of a severe course and complications of novel coronavirus infection.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

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