Lipid metabolism disorders in patients with hypertension and diabetes mellitus: development and current treatment options

Author:

Podzolkov V. I.1ORCID,Tarzimanova A. I.1ORCID,Abramova A. A.1ORCID,Vetluzhskaya M. V.1ORCID,Medvedev I. D.1ORCID,Loria I. Zh.1ORCID

Affiliation:

1. I. M. Sechenov First Moscow State Medical University

Abstract

The article presents the main mechanisms of development of lipid metabolism disorders and endothelial dysfunction in patients with hypertension (HTN) and type 2 diabetes (T2D), and their contribution to cardiovascular events. Modern approaches to the treatment of hypertension and dyslipidemia in people with type 2 diabetes are considered from the standpoint of the latest clinical guidelines, focusing on fixed-dose combinations as a means of an integrated approach to managing risk factors in comorbid patients. Data are presented on the efficacy and safety of fixed-dose combination of lisinopril, amlodipine and rosuvastatin in patients with hypertension and T2D.

Publisher

Silicea - Poligraf, LLC

Subject

Cardiology and Cardiovascular Medicine,Education

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