Pharmacoeconomic analysis of costs for radiopaque agents and a method to minimize them

Abstract

The aim of the work is to minimize the costs of a multidisciplinary hospital in the city of Volgograd for radiopaque substances. Materials and research methods: In the first part, the costs of the hospital for the purchase of x-ray contrast medications were studied and the average cost of direct costs for radiopaque agents for one coronary angiography procedure was determined. In the second part, a comparative analysis of the cost of radiopaque agents presented on the Russian market was carried out on the basis of the State Register of Selling Prices. Results of the study and their discussion: A retrospective analysis of 147 case histories of patients undergoing percutaneous coronary intervention showed that the average volume of radiopaque drug during coronary angiography was (126.19 36.35) ml. In 66 (44.9 %) patients, more than 100 ml was used per procedure. For one coronary angiography procedure, on average (126 ml of contrast), 1927.8 rubles were spent for a radiopaque preparation. Among the radiopaque drugs recommended for coronary angiography, according to the state register of maximum ex-works prices, Iohexol preparations 350 mg/ml of Russian production had the lowest cost. Conclusions: Procurement of domestic preparations Iohexol 350 mg/ml, 100 ml bottles will reduce the cost of percutaneous coronary intervention.