CHANGES IN FUNDUS AUTOFLUORESCENCE IN YOUNG SUBJECTS WITH DIFFERENT TYPESOF REFRACTION. REPORT 1

Abstract

Purpose:to assess the state of the macular region of the retina using the study of autofluorescence (AF) of theeye fundus in young subjects with high visual acuity and different types of clinical refraction.Material and methods.104 healthy volunteers (208 eyes), 70 females and 34 males, aged 20 to 30 years, average age (24,5± 0,4) годаy.о., were examined. All patients had high visual acuity (1,0 and higher) and there were no signs of pathology in the macular region, which was established ophthalmoscopically and confirmed by optical coherence tomography (OCT) data. Such methods of the examination were performed in all subjects as visometry with correction, refractometry, ophthalmobiomi-ocroscopy with Goldmann's lens, OCT in the 3D mode of the macular region of the fundus and the study of fundus-AF with typing on known patterns: normal pattern, minimal changes, focal changes and reticular pattern. The analysis was carried outin10 subgroups depending on the type, the degree of clinical refraction and the presence of astigmatism.Results.4 main patterns of AF were identified in the examined subjects: normal, minimal changes, focal changes and reticular. The most common pattern in all refractive groups was the reticular pattern, the frequency of which ranged from 41,7 to 88,9%. The least common pattern was normal, the frequency of which ranged from 4,2 to 33,3%. A significant differencebetween the values of the thickness of the retina in the foveal zone with the reticular pattern and its average group value in different refractive groups was not found.Conclusion.In young subjects with high visual acuity without clinical manifestation of pathology of the macular zone, AF-patterns other than the normal picture may be present. The reticular pattern is noted as the most common in all analyzed groups with various types of refraction. Further studies of early changes in fundus AF may make it possible to determine thepredictors of the development of dystrophic pathology of the macular zone.