1. State Key Laboratory of Respiratory Diseases and Guangzhou Institute of Respiratory Diseases; Guangzhou Guangdong China
2. The First Affiliated Hospital of Guangzhou Medical University; Guangzhou Guangdong China
3. Keenan Research Centre for Biomedical Science of St. Michael's Hospital; Toronto Ontario Canada
4. Department of Medicine; University of Toronto; Toronto Ontario Canada
5. Department of Anesthesia; University of Toronto; Toronto Ontario Canada. Department of Physiology; University of Toronto; Toronto Ontario Canada