Antimicrobial Sensitivity of Pseudomonas aeruginosa to Aztreonam, Amoxicillin, Erythromycin, Carbenicillin, Norfloxacin, Chloramphenicol, Gentamycin and Azithromycin after Exposure to Radiation Emitted from Radioactive Sources, Lasers and Exposure to Magn

Author:

Mohammed Nebras Rada

Abstract

Objective: The aim of this study to assess the sensitivity of P. aeruginosa for ATM, AML, E, CAR, NOR, CL, CN and AZM after exposure to radiation emitted from radioactive sources, Lasers and exposure to magnetized water.  Study design: Cross-sectional in descriptive study design with case–control in analytical study design  Backgrounds: P. aeruginosa gram negative bacteria occasion distinct kinds of contagion including epidermis, optics, ears, respiratory tract, urinary tract, intestines derived sepsis, soft tissues, skeleton and joint contagion. Radiation including ionizing and non-ionization depending on the energy of the radiated particles emitted Alpha, Beta and Gamma rays from different radioactive sources.  Methodology: Study populations and bacterial deposition and identification of P. aeruginosa. Exposure P. aeruginosa to radiation at different times and doses. Antimicrobial susceptibility test for ATM, AML, E, CAR, NOR, CL, CN and AZM after exposure to radiation emitted from radioactive sources, Lasers and magnetized water.  Results: After exposing P. aeruginosa to the Na23, CO60, Cs137 and Sr90 radioactive source without or without aluminum for (1,2,3) hr., the bacteria were examined for antibiotics and the results are high sensitivity to NOR, ATM, CAR. As well as, exposure to Nd: YAG laser in (10, 20) min. with exposure to magnetized water which show high sensitive to NOR and ATM antibiotics.  Conclusions: The radioactive sources, Nd: YAG laser and magnetic water have a strong effect on bacteria and their sensitivity to antibiotics, so that their sensitivity rate increased very significantly compared to before exposure. The most effective antibiotics in killing bacteria after exposure are Aztreonam, Norfloxacin, Carbenicillin and Gentamycin (ATM, NOR, CAR and CN). 

Publisher

AMO Publisher

Reference20 articles.

1. Aghamollaei, H., Moghaddam, M. M., Kooshki, H., Heiat, M., Mirnejad, R., & Barzi, N. S. (2015). Detection of Pseudomonas aeruginosa by a triplex polymerase chain reaction assay based on lasI/R and gyrB genes. Journal of infection and public health, 8(4), 314–322. https://doi.org/10.1016/j.jiph.2015.03.003

2. Akasaka, T., Tanaka, M., Yamaguchi, A., & Sato, K. (2001). Type II topoisomerase mutations in fluoroquinolone-resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999: role of target enzyme in mechanism of fluoroquinolone resistance. Antimicrobial agents and chemotherapy, 45(8), 2263–2268. https://doi.org/10.1128/AAC.45.8.2263-2268.2001

3. Chen, J., Su, Z., Liu, Y., Wang, S., Dai, X., Li, Y., Peng, S., Shao, Q., Zhang, H., Wen, P., Yu, J., Huang, X., & Xu, H. (2009). Identification and characterization of class 1 integrons among Pseudomonas aeruginosa isolates from patients in Zhenjiang, China. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 13(6), 717–721. https://doi.org/10.1016/j.ijid.2008.11.014

4. Clinical and Laboratory Standard Institute (CLSI) (2020).

5. El Zowalaty, M. E., Al Thani, A. A., Webster, T. J., El Zowalaty, A. E., Schweizer, H. P., Nasrallah, G. K., Marei, H. E., & Ashour, H. M. (2015). Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies. Future microbiology, 10(10), 1683–1706. https://doi.org/10.2217/fmb.15.48

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3