Preventing Small-for-size Syndrome in Living Donor Liver Transplantation: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference-Reference-Cited by-全球学者库

Preventing Small-for-size Syndrome in Living Donor Liver Transplantation: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference

Published:2023-08-28 Issue:10 Volume:107 Page:2203-2215
ISSN:0041-1337
Container-title:Transplantation
language:en
Short-container-title:

Author:

Hakeem Abdul Rahman¹,Mathew Johns Shaji²,Aunés Carmen Vinaixa³⁴,Mazzola Alessandra⁵,Alconchel Felipe⁶⁷,Yoon Young-In⁸,Testa Giuliano⁹,Selzner Nazia¹⁰,Sarin Shiv Kumar¹¹,Lee Kwang-Woong¹²,Soin Arvinder¹³,Pomposelli James¹⁴,Menon Krishna¹⁵,Goyal Neerav¹⁶,Kota Venugopal¹⁷,Abu-Gazala Samir¹⁸,Rodriguez-Davalos Manuel¹⁹,Rajalingam Rajesh²⁰,Kapoor Dharmesh²¹,Durand Francois²²,Kamath Patrick²³,Jothimani Dinesh²⁰,Sudhindran Surendran²⁴,Vij Vivek²⁵,Yoshizumi Tomoharu²⁶,Egawa Hiroto²⁷,Lerut Jan²⁸,Broering Dieter²⁹,Berenguer Marina³⁰,Cattral Mark¹⁰,Clavien Pierre-Alain³¹,Chen Chao-Long³²,Shah Samir³³,Zhu Zhi-Jun³⁴³⁵,Ascher Nancy³⁶,Bhangui Prashant¹³,Rammohan Ashwin²⁰,Emond Jean³⁷,Rela Mohamed²⁰

Affiliation:

1. Department of Hepatobiliary and Liver Transplant Surgery, St. James’s University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.

2. Department of GI, HPB & Multi-Organ Transplant, Rajagiri Hospitals, Kochi, India.

3. Hepatología y Trasplante Hepático, Servicio de Medicina Digestiva, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

4. CIBERehd, Instituto de Salud Carlos III, Madrid, Spain.

5. Sorbonne Université, Unité Médicale de Transplantation Hépatique, Hépato-gastroentérologie, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.

6. Department of Surgery and Transplantation, Virgen de la Arrixaca University Hospital, Murcia, Spain.

7. Biomedical Research Institute of Murcia, IMIB-Pascual Parrilla, Murcia, Spain.

8. Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, Seoul, South Korea.

9. Department of Abdominal Transplantation, Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX.

10. Multi-Organ Transplant Program, Ajmera Transplant Center, University of Toronto, Toronto, ON, Canada.

11. Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.

12. Department of Surgery, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, South Korea.

13. Medanta Institute of Liver Transplantation and Regenerative Medicine, Medanta-The Medicity, Delhi, NCR, India.

14. University of Colorado School of Medicine, Division of Transplant Surgery, Department of Surgery, Aurora, CO.

15. Institute of Liver Diseases, King’s College Hospital, London, United Kingdom.

16. Liver Transplant and Hepato-Pancreatobiliary Surgery Unit (LTHPS), Indraprastha Apollo Hospital, New Delhi, India.

17. Department of HPB Surgery and Liver Transplantation, Yashoda Hospitals, Secunderabad, Hyderabad, Telangana, India.

18. Division of Transplant Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

19. Liver Center, Primary Children’s Hospital; Transplant Services, Intermountain Transplant Center, Primary Children’s Hospital, Salt Lake City, UT.

20. Institute of Liver Disease and Transplantation, Dr Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.

21. Department of Hepatology and Liver Transplantation, Yashoda Hospitals, Secunderabad, Hyderabad, Telangana, India.

22. Hepatology and Liver Intensive Care, Hospital Beaujon, Clichy University Paris Cité, Paris, France.

23. Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

24. Department of Gastrointestinal Surgery and Solid Organ Transplantation, Amrita Institute of Medical Sciences, Kochi, India.

25. Department of HPB Surgery and Liver Transplantation, Fortis Group of Hospitals, New Delhi, India.

26. Department of Surgery and Science, Kyushu University, Fukuoka, Japan.

27. Department of Surgery, Tokyo Women’s Medical University, Tokyo, Japan.

28. Institute for Experimental and Clinical Research (IREC), Université catholique Louvain (UCL), Brussels, Belgium.

29. Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

30. Liver Unit, Ciberehd, Instituto de Investigación Sanitaria La Fe, Hospital Universitario y Politécnico La Fe, Universidad Valencia, Valencia, Spain.

31. Department of Surgery and Transplantation, Swiss HPB Center, University Hospital Zurich, Zürich, Switzerland.

32. Liver Transplantation Centre, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

33. Department of Hepatology, Institute of Liver Disease, HPB Surgery and Transplant, Global Hospitals, Mumbai, India.

34. Liver Transplantation Center, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

35. Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing, China.

36. Department of Surgery, University of California, San Francisco, San Francisco, CA.

37. Liver and Abdominal Transplant Surgery, Columbia University Irving Medical Center, New York, NY.

Abstract

Small-for-size syndrome (SFSS) is a well-recognized complication following liver transplantation (LT), with up to 20% developing this following living donor LT (LDLT). Preventing SFSS involves consideration of factors before the surgical procedure, including donor and recipient selection, and factors during the surgical procedure, including adequate outflow reconstruction, graft portal inflow modulation, and management of portosystemic shunts. International Liver Transplantation Society, International Living Donor Liver Transplantation Group, and Liver Transplant Society of India Consensus Conference was convened in January 2023 to develop recommendations for the prediction and management of SFSS in LDLT. The format of the conference was based on the Grading of Recommendations, Assessment, Development, and Evaluation system. International experts in this field were allocated to 4 working groups (diagnosis, prevention, anesthesia, and critical care considerations, and management of established SFSS). The working groups prepared evidence-based recommendations to answer-specific questions considering the currently available literature. The working group members, independent panel, and conference attendees served as jury to edit and confirm the final recommendations presented at the end of the conference by each working group separately. This report presents the final statements and evidence-based recommendations provided by working group 2 that can be implemented to prevent SFSS in LDLT patients.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Transplantation

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