Outwitting the Blood-Brain Barrier for Therapeutic Purposes: Osmotic Opening and Other Means

Author:

KrolI Robert A.1,Neuwelt Edward A.12,Neuwelt Edward A.2

Affiliation:

1. Department of Neurology, Oregon Health Sciences University, and Veterans Administration Medical Center, Portland, Oregon

2. Department of Surgery, Oregon Health Sciences University, and Veterans Administration Medical Center, Portland, Oregon

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

Reference79 articles.

1. Transporting therapeutics across the blood-brain barrier;Abbott;Mol Med Today,1996

2. Boron neutron capture therapy of brain tumors: Enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption;Barth;Cancer Res,1997

3. Protein kinases as mediators of fluid shear stress stimulated signal transduction in endothelial cells: A hypothesis for calcium-dependent and calcium-independent events activated by flow;Berk;J Biomech,1995

4. A review of hyperosmotic blood-brain barrier disruption in seven experimental brain tumor models;Blasberg,1990

5. Convection-enhanced delivery of macromolecules in the brain;Bobo;Proc Natl Acad Sci U S A,1994

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