Population pharmacokinetics and dosing optimization of metformin in Chinese patients with type 2 diabetes mellitus

Author:

Li Ling,Guan Ziwan,Li Rui,Zhao Wei,Hao Guoxiang,Yan Yan,Xu Yuedong,Liao Lin,Wang Huanjun,Gao Li,Wu Kunrong,Gao Yuxia,Li Yan

Funder

National key research project precision special medical integrated application demonstration system construction project

Jinan Science and Technology Bureau

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference35 articles.

1. Mechanism by which metformin reduces glucose production in type 2 diabetes;Hundal;Diabetes,2000

2. Effect of metformin on oxidative stress, nitrosative stress and inflammatory biomarkers in type 2 diabetes patients;Chakraborty;Diabetes Res Clin Pract,2011

3. Effectiveness of metformin on weight loss in non-diabetic individuals with obesity;Seifarth;Exp Clin Endocrinol Diabetes,2013

4. The effect of metformin on carotid intima-media thickness (CIMT): a systematic review and meta-analysis of randomized clinical trials;Chen;Eur J Pharmacol,2020

5. Metformin pathways: pharmacokinetics and pharmacodynamics;Gong;Pharmacogenet Genomics,2012

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