Pulmonary mucoepidermoid carcinoma in children: a rare diagnosis not to be overlooked – case report

Author:

Dardouri Teheni1,Ezzine Abir1,Ben Fredj Maha1,Boudriga Hajer1,Mensi Sihem1,Ayadi Aïda2,Abroug Saoussen3,Nouira Manel1,Chatti Kaouthar4

Affiliation:

1. Laboratoire De Biophysique Métabolique Et Pharmacologie Appliquée, Department of Nuclear Medicine, Sahloul University Hospital, Université De Sousse

2. Department of Pathology, Abderrahmen Memi University Hospital, Tunis, Tunisia

3. Department of Pediatrics

4. Department of Nuclear Medicine, Laboratoire De Technologie Et Imagerie Médicale, Sahloul University Hospital, Université De Monastir, Sousse

Abstract

Introduction and importance: Pulmonary mucoepidermoid carcinoma (PMEC) in children is a rare entity. The diagnosis is often unrecognized, often treated as pneumonia, a more frequent diagnosis at this age. Case presentation: The authors report in this article, the case of a 12-year-old child with a clinical history of chronic cough evolving for 6 months with recurrent episodes of pneumonia. The presence of a foreign body was suggested on the thoracic computed tomography (CT). PMEC was histopathologically determined on biopsy. Fluorine-18-fluorodesoxyglucose positron emission tomography (18 F-FDG PET)/CT was performed as part of the extension work-up prior to surgical management. Clinical discussion: Preoperative imaging with 18F-FDG PET/CT seems to be a valuable tool for predicting tumor grade, nodal stage, and postsurgical prognosis in mucoepidermoid carcinoma. PMEC patients with high 18F-FDG PET/CT uptake may need extensive mediastinal lymph node dissection and adjuvant therapy. Conclusion: PMEC has different presentations depending on the degree of tumor differentiation on PET/CT whose input in the management of these rare cancers requires further studies.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine,Surgery

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