Management of Gastrointestinal Symptoms in Parkinson’s Disease

Author:

Pasricha Trisha S.12,Guerrero-Lopez Ingrid L.3,Kuo Braden12

Affiliation:

1. Division of Gastroenterology, Massachusetts General Hospital

2. Harvard Medical School, Boston, MA

3. Faculty of Medicine, University of Vic-Central University of Catalonia, Vic, Spain

Abstract

Gastrointestinal symptoms in Parkinson’s disease (PD) are among the most prevalent and debilitating of complications and present unique diagnostic and management challenges. Patients with PD commonly experience dysphagia, nausea, bloating, and constipation related to pathologic involvement of the enteric nervous system. In turn, gastrointestinal complications may impact motor fluctuations and the efficacy of levodopa therapy. This review will explore the common gastrointestinal manifestations of PD with an emphasis on clinical presentation, workup, and treatment strategies.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Gastroenterology

Reference110 articles.

1. Gastrointestinal dysfunction and neuropathologic correlations in Parkinson disease;Mrabet;J Clin Gastroenterol,2016

2. Association of motor and nonmotor symptoms with health-related quality of life in a large online cohort of people with Parkinson disease;Bock;Neurology,2022

3. Gastrointestinal dysfunction impact on life quality in a cohort of Russian patients with Parkinson’s disease I-III H&Y stage;Pilipovich;Parkinsons Dis,2022

4. A bidirectional relationship between anxiety, depression and gastrointestinal symptoms in Parkinson’s disease;Jones;Clin Park Relat Disord,2021

5. Upper and lower gastrointestinal symptom association and duration preceding Parkinson’s disease;Gadi;Gastro Hep Adv,2023

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3