Cellulite Pathophysiology and Psychosocial Implications

Author:

Bass Lawrence S.12,Hibler Brian P.3,Khalifian Saami4,Shridharani Sachin M.56,Klibanov Olga M.7,Moradi Amir4

Affiliation:

1. Bass Plastic Surgery, PLLC, New York, New York;

2. Division of Plastic Surgery, Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York;

3. Schweiger Dermatology Group, New York, New York;

4. Moradi MD, San Diego, California;

5. LUXURGERY, New York, New York;

6. Washington University in St. Louis, School of Medicine, St. Louis, Missouri;

7. Real World Solutions, IQVIA, Parsippany, New Jersey.

Abstract

BACKGROUND Cellulite is a highly prevalent aesthetic condition in postpubertal women. OBJECTIVE The objective of this article was to describe the latest data on the pathophysiology of cellulite and to highlight the psychosocial aspects that should be considered when treating cellulite. METHODS A roundtable meeting was convened to discuss and share views on the latest data on the pathophysiology and psychosocial aspects of cellulite. The participants' experience helped guide a narrative review on this topic. RESULTS The pathophysiology of cellulite primarily involves fibrous septal changes. Strategies targeting the fibrous septa have shown the most consistent efficacy, while showing inconsistent or short-term results when targeting the other components of cellulite, such as decreased dermal thickness, vascular alterations, and inflammation. Female sex, increased age, and high body mass index contribute to cellulite pathophysiology. CONCLUSION Patients seeking treatment for cellulite are willing to endure numerous treatments, high cost, temporary and/or delayed results, and invasive procedures with potential adverse effects. Psychological discomfort has been reported among patients with cellulite, and understanding their behaviors and psychological characteristics can help clinicians provide better care to these patients seeking treatment.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Dermatology,General Medicine,Surgery

Reference41 articles.

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2. Cellulite: advances in treatment: facts and controversies;Emanuele;Clin Dermatol,2013

3. Cellulite: a review with a focus on subcision;Friedmann;Clin Cosmet Investig Dermatol,2017

4. Cellulite: a new treatment approach combining subdermal Nd: YAG laser lipolysis and autologous fat transplantation;Goldman;Aesthet Surg J,2008

5. Assessment of psychological, psychiatric, and behavioral aspects of patients with cellulite: a pilot study;Hexsel;Surg Cosmet Dermatol,2012

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