Author:
Ren Chengcheng,Li Xiaobo,Wang Tianzhen,Wang Guangyu,Zhao Ci,Liang Tian,Zhu Yuanyuan,Li Minghui,Yang Chao,Zhao Yunlong,Zhang Guang-mei
Abstract
AbstractLong noncoding RNAs (lncRNAs) are longer than 200-nucleotide, noncoding transcripts in length, have a variety of biological functions, and are closely associated with tumor development. Ovarian cancer, as 1 of the 3 common gynecological malignancies, is the leading cause of death in women with gynecological malignant tumor. In this study, a review of the literature found that lncRNAs H19, LSINCT5, and XIST have a close relationship to the development of ovarian cancer occurrence, growth, invasion, and metastasis, and they can promote ovarian cancer cell proliferation. Hence, in this article, the progress of above-mentioned 3 kinds of lncRNAs in ovarian cancer was reviewed and designed to help in the diagnosis, treatment, and prognosis of ovarian cancer.
Subject
Obstetrics and Gynaecology,Oncology
Cited by
68 articles.
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