High hyperopic LASIK with reduction of corneal prolateness to control-induced spherical aberration

Abstract

Purpose: To evaluate visual outcomes of high hyperopic laser in situ keratomileusis (LASIK), using corneal aspherization to control the induced spherical aberration. Setting: Fondation Ophtalmologique Adolphe de Rothschild, Paris, France. Design: Prospective interventional case series. Methods: Prospective interventional study of consecutive high hyperopes (≥+3 diopters [D] of spherical equivalent [SE]) undergoing LASIK with the WaveLight FS200 femtosecond and EX500 excimer laser platform. An aspheric ablation profile (planned change in corneal asphericity ΔQ = +0.2) was delivered using the Custom-Q nomogram on an optical zone of ≥6.5 mm centered near the corneal vertex. Uncorrected corrected distance visual acuity (UDVA) and corrected distance visual acuity, as well as changes in SE, corneal asphericity (ΔQ), and higher-order aberrations, were analyzed preoperatively and on day 1, 1, 3, 6, and 12 months. Results: 117 eyes of 63 patients (mean age of 30.1 ± 5.6 years) were included. Preoperatively and at 12 months postoperatively, the mean SE was 5.1 ± 1.1 D and 0.00 ± 0.7 D, respectively. 88% of eyes achieved 0 logMAR or better UDVA at 12 months. 1 month postoperatively, there was a statistically significant induction of positive spherical aberration decreasing progressively and significantly until the last visit (preop SA4 = 0.09 ± 0.11 μm, day 1 SA4 = 0.30 ± 0.32 μm, 12 months SA4 = 0.08 ± 0.21 μm, P = .056). 2 eyes needed enhancement at 12 months. Conclusions: LASIK for high levels of hyperopia showed good outcomes mainly due to aspheric-customized ablation profile with a change of ΔQ = +0.2 in corneal asphericity.