A patient with neuropathy and ataxia: what do I have to consider?

Abstract

Purpose of reviewAn increasing number of peripheral neuro(no)pathies are identified as involving other components of the neurological system, particularly those that further impair balance. Here we aim to outline an evidence-based approach to the diagnosis of patients who present with a somatosensory disorder which also involves at least one other area of neurological impairment such as the vestibular, auditory, or cerebellar systems.Recent findingsDetailed objective investigation of patients who present with sensory impairment, particularly where the degree of imbalance is greater than would be expected, aids the accurate diagnosis of genetic, autoimmune, metabolic, and toxic neurological disease.SummaryDiagnosis and management of complex somatosensory disorders benefit from investigation which extends beyond the presenting sensory impairment.