The Retrospective Implementation of Standardized In Utero HIV Exposure Definitions Using Routinely Collected Public Sector Data Across the Western Cape Province, South Africa

Author:

de Beer Shani T.123ORCID,Davies Mary-Ann124,Phelanyane Florence12,Jones Hayley E.3,Ingle Suzanne M.3,Eley Brian S.5,Anderson Kim1,Heekes Alexa12,Kalk Emma1,Mendelsohn Andrea26,Boulle Andrew47,Slogrove Amy L.7

Affiliation:

1. From the Centre for Infectious Disease Epidemiology and Research

2. Health Intelligence Directorate, Western Cape Government Health and Wellness, Cape Town, South Africa

3. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

4. Division of Public Health Medicine

5. Paediatric Infectious Diseases Unit, Red Cross War Memorial Children’s Hospital and the Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa

6. Division of Family Medicine, School of Public Health, University of Cape Town, Cape Town, South Africa

7. Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Worcester, South Africa.

Abstract

Using the Data Evaluation and Preparation for HIV-Exposed Uninfected Child Cohorts project’s standardized child HIV exposure definitions, 64%, 64% and 90% of children exposed to HIV in utero could be classified as HIV-uninfected with moderate or high certainty at the ages of 1 and 3 years and at the time of first infectious disease hospitalization, respectively. These definitions can be applied retrospectively to routine datasets with linked mother-child data.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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