The disease burden of respiratory syncytial virus in Infants

Author:

Munro Alasdair P.S.12,Martinón-Torres Federico345,Drysdale Simon B.67,Faust Saul N.12

Affiliation:

1. NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust

2. Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK

3. Translational Paediatrics and Infectious Diseases, Hospital Clínico Universitario and Universidad de Santiago de Compostela

4. Genetics, Vaccines and Paediatric Infectious Diseases Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago and Universidad de Santiago de Compostela (USC), Galicia

5. CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain

6. Centre for Neonatal and Paediatric Infection, Institute for Infection and Immunity, St George's, University of London

7. Department of Paediatrics, St George's University Hospital NHS Foundation Trust, London, UK

Abstract

Purpose of review To describe the current global burden of respiratory syncytial virus (RSV) in infants and its implications for morbidity, health resources and economic costs. Recent findings New prophylactic therapies are on the horizon for RSV in the form of long-acting monoclonal antibodies suitable for healthy infants and maternal immunizations. Summary Despite being responsible for significant global infant morbidity and mortality, until recently there have been no effective therapeutics available for healthy infants to protect them from RSV. Several new drugs are likely to be available within the next few years which could help relieve a huge burden on healthcare systems over the coming winters.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Microbiology (medical)

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