Liver transplantation for pediatric genetic and metabolic disorders-Reference-Cited by-同舟云学术

Liver transplantation for pediatric genetic and metabolic disorders

Published:2024-08-23 Issue:6 Volume:31 Page:803-814
ISSN:1527-6465
Container-title:Liver Transplantation
language:en
Short-container-title:

Author:

Hassan Sara¹^ORCID,Anouti Ahmad²^ORCID,Tan Queenie K.G.³^ORCID,Wangensteen Kirk⁴^ORCID,Aqul Amal⁵^ORCID

Affiliation:

1. Division of Pediatric Gastroenterology, Department of Pediatrics, Hepatology and Nutrition, Mayo Clinic, Rochester, Minnesota, USA

2. Department of Pediatrics, University of Texas Southwestern, Dallas, Texas, USA

3. Division of Medical Genetics, Department of Clinical Genomics, Mayo Clinic, Rochester, Minnesota, USA

4. Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA

5. Division of Pediatric Gastroenterology, Department of Pediatrics, Hepatology and Nutrition, University of Texas Southwestern, Dallas, Texas, USA

Abstract

Pediatric genetic and metabolic liver diseases comprise a broad spectrum of conditions and represent the second most common indication for liver transplantation following biliary atresia. The decision to transplant can be challenging and requires consideration of several factors, including hepatic involvement, extrahepatic manifestations, and anticipated posttransplant outcomes. This review examines pediatric genetic and metabolic liver diseases, their pathophysiology, clinical presentation, and the role of liver transplantation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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