The HIV-1 Reverse Transcriptase M184I Mutation Enhances the E138K-Associated Resistance to Rilpivirine and Decreases Viral Fitness-Reference-Cited by-同舟云学术

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The HIV-1 Reverse Transcriptase M184I Mutation Enhances the E138K-Associated Resistance to Rilpivirine and Decreases Viral Fitness

Published:2012-01-01 Issue:1 Volume:59 Page:47-54
ISSN:1525-4135
Container-title:JAIDS Journal of Acquired Immune Deficiency Syndromes
language:en
Short-container-title:

Author:

Kulkarni Rima,Babaoglu Kerim,Lansdon Eric B.,Rimsky Laurence,Van Eygen Veerle,Picchio Gaston,Svarovskaia Evguenia,Miller Michael D.,White Kirsten L.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Infectious Diseases

Reference35 articles.

1. The effect of transmitted HIV-1 drug resistance on pre-therapy viral load.;Harrison;AIDS,2010

2. Clinical significance of human immunodeficiency virus type 1 replication fitness.;Dykes;Clin Microbiol Rev,2007

3. Resistance to protease inhibitors.;Kuritzkes;J HIV Ther,2002

4. The A62V and S68G Mutations in HIV-1 Reverse Transcriptase Partially Restore the Replication Defect Associated With the K65R Mutation.;Svarovskaia;J Acquir Immune Defic Syndr,2008

5. Secondary mutations in viruses resistant to HIV-1 integrase inhibitors that restore viral infectivity and replication kinetics.;Nakahara;Antiviral Res,2009

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3. Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties;Journal of Medicinal Chemistry;2023-01-18

4. Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine;Proceedings of the National Academy of Sciences;2022-07-19

5. High efficacy of switching to bictegravir/emtricitabine/tenofovir alafenamide in people with suppressed HIV and preexisting M184V/I;AIDS;2022-04-23

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