Differentiating Brown Tumor From Bone Metastasis in Parathyroid Cancer Using 18F-FDG PET and 99mTc-MIBI SPECT-Reference-Cited by-同舟云学术

Differentiating Brown Tumor From Bone Metastasis in Parathyroid Cancer Using 18F-FDG PET and 99mTc-MIBI SPECT

Published:2024-02-22 Issue:5 Volume:49 Page:444-446
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Tsukamoto Suzune¹,Kawabata Kazuna¹,Kawamura Hitomi²,Takata Kuniaki³,Hosono Makoto⁴

Affiliation:

1. Department of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo

2. Department of Diagnostic Radiology, Graduate School of Medicine, Kyoto University, Kyoto

3. Department of Otolaryngology, Head and Neck Surgery, Tenri Hospital, Nara

4. Department of Radiology, Kindai University Faculty of Medicine, Osaka, Japan.

Abstract

Abstract A 69-year-old woman presented with a right clavicle pain. CT revealed a pathological fracture of the right clavicle, multiple osteolytic lesions, and a left cervical mass. 18F-FDG PET/CT demonstrated a marked FDG uptake in the cervical mass and osteolytic lesions indicative of metastatic parathyroid cancer. 99mTc-MIBI SPECT/CT revealed either faint or no uptake in the osteolytic lesions. However, a histopathological analysis after a parathyroidectomy and right clavicle biopsy confirmed the diagnosis of parathyroid cancer and the presence of benign brown tumors secondary to hyperparathyroidism. Postoperative imaging showed sclerotic change and a decreased FDG uptake in the bone lesions.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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