Microsurgical Peritoneovenous Bypass for the Treatment of Recalcitrant Chylous Ascites

Author:

Klifto Kevin M.12,Card Elizabeth B.2,Itkin Maxim3,Kovach Stephen J.2

Affiliation:

1. Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Missouri School of Medicine

2. Division of Plastic Surgery, Department of Surgery

3. Department of Radiology, University of Pennsylvania Perelman School of Medicine.

Abstract

Background: New treatments for recalcitrant chylous ascites are needed to avoid sequelae associated with increased intraabdominal pressures, chyle loss, and diminished quality of life. An autologous microsurgical technique was developed to treat recalcitrant chylous ascites and restore normal physiology. Methods: A retrospective case series was performed for patients with recalcitrant chylous ascites surgically treated from 2018 to 2020. The authors included all patients with recalcitrant chylous ascites refractory to current standard-of-care interventions such as diet modifications, pharmacologic therapies, and peritoneovenous mechanical shunts. All were treated with microsurgical peritoneovenous bypass with a minimum follow-up of 12 months. Results: Six patients were included over a 2-year period. Surgery was aborted for two patients (33%) with intraoperative venous reflux of the deep inferior epigastric vein, negative on preoperative ultrasound. One patient had a successful reoperation using the contralateral greater saphenous vein; the other elected for a chronic indwelling drain for chyle drainage. Among the five successful procedures (83%), ascites drainage decreased from a median preoperative volume of 1 L/day to postoperative volume of 0.06 L/day. Median hospital length of stay was 7 days (range, 212 to 194 days). Three patients had one complication each, including vancomycin-resistant Enterococcus, spontaneous bacterial peritonitis, and pulmonary embolism. All complications resolved with additional interventions. Median follow-up was 13.5 months (range, 12 to 27 months). Conclusion: Microsurgical peritoneovenous bypass was a reliable and reproducible autologous surgery for the treatment of recalcitrant chylous ascites at a minimum follow-up of 12 months. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Surgery

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