Antibiotic prophylaxis in trauma: GAIS, SIS-E, WSIS, AAST, WSES guidelines

Author:

Coccolini Federico1,Sartelli Massimo2,Sawyer Robert3,Rasa Kemal4,Ceresoli Marco5,Viaggi Bruno6,Catena Fausto7,Damaskos Dimitrios8,Cicuttin Enrico9,Cremonini Camilla1,Moore Ernest E.10,Biffl Walter L.11,Coimbra Raul12ORCID

Affiliation:

1. General, Emergency and Trauma Surgery Dept., Pisa University Hospital, Pisa, Italy

2. General and Emergency Surgery, Macerata Hospital, Macerata, Italy

3. Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo

4. Department of Surgery, Anadolu Medical Center, Kocaali, Turkey

5. General, Emergency and Trauma Surgery Dept., Monza University Hospital, Monza, Italy

6. ICU Department, Careggi Hospital, Firenze, Italy

7. Emergency and Trauma Surgery, Maggiore Hospital, Parma, Italy

8. General and Emergency Surgery, NHS Lothian, Edinburgh, UK

9. General, Emergency and Trauma Surgery Department, Pavia University Hospital, Pavia, Italy

10. Ernest E Moore Shock Trauma Center at Denver Health, Denver (Colorado), USA

11. Trauma Surgery Department, Scripps Memorial Hospital, La Jolla, California, USA

12. Division of Trauma and Acute Care Surgery and Comparative Effectiveness and Clinical Outcomes Research Center - CECORC, Riverside University Health System, Moreno Valley, California

Abstract

Abstract Trauma is a complex disease, and the use of antibiotic prophylaxis (AP) in trauma patients is common practice. However, considering the increasing rates of antibiotic resistance, AP use should be questioned and limited only to specific cases. Antibiotic stewardship is of paramount importance in fighting resistance spread. Definitive rules or precise indications about antibiotic prophylaxis in trauma remain unclear. The present manuscript describes the indications of antibiotic prophylaxis in traumatic lesions to the head, brain, torso, maxillo-facial, extremities, skin, and soft tissues endorsed by the Global Alliance for Infection in Surgery (GAIS), Surgical Infection Society Europe (SIS-E), World Surgical Infection Society (WSIS), American Association for the Surgery of Trauma (AAST), World Society of Emergency Surgery (WSES).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Critical Care and Intensive Care Medicine,Surgery

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