Endometrioid adenofibroma of ovary: A case report and review of literature

Author:

Tong Hai-Chao1,Li Ying-Chun1,Li Le-Yao1,Xu Hong-Tao1,Ma Shuang2,Zhang Wan-Lin3,Wildes Tyler4,Yang Lian-He1ORCID,Wang Endi4

Affiliation:

1. Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, Liaoning, China

2. Department of Neurology, Sheng Jing Hospital of China Medical University, Shenyang, Liaoning, China

3. Department of Pathology, Hebei Petro China Central Hospital, Langfang, Hebei, China

4. Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA.

Abstract

Rationale: Endometrioid adenofibroma is a benign epithelial neoplasm of the ovary, most of which are often unilateral. The symptoms of endometrioid adenofibroma are often nonspecific and misleading. Therefore, a full understanding of the characteristics, diagnosis, and treatment methods of this disease is of great importance. In this study, we report a 34-year-old woman who was found with an unidentified mass on the right ovary during the physical examination 3 years ago with nosymptoms or signs. Patient concerns: A 34-year-old Chinese female was found with an unidentified 6 cm mass on the right ovary for 3 years that presented with no symptoms or signs. Diagnosis: Pelvic ultrasound revealed a 6 cm cystic solid mixed mass on the right ovary. Through histological and immunohistochemical examinations, the tumor mass was finally diagnosed as endometrioid adenofibroma of ovary. Interventions: To confirm the diagnosis, the ovarian tumor was laparoscopically resected. Outcomes: The patient returned to hospital after 3 months with no recurrence or postoperative complications. Lessons: Endometrioid adenofibroma is a benign epithelial neoplasm of the ovary. Complete surgical resection is required and rare cases can recur. Postsurgical pathologic and immunohistochemical testing can confirm a diagnosis of endometrioid adenofibroma. It is important to understand of the key points of differential diagnosis of the disease due to the different prognosis and clinical treatment.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference19 articles.

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2. Ovarian clear cell adenofibroma of low malignant potential developing into clear cell adenocarcinoma.;Yin;Int J Surg Pathol,2018

3. Proliferating endometrioid cystadenofibroma of the ovary. Report of a case in a teenager.;Nasca;Diagn Gynecol Obstetr,1982

4. Large functional benign endometroid cystadenofibroma of the ovary leading to endometrial cystic glandular hyperplasia and postmenopausal bleeding.;Singh;BMJ Case Rep,2013

5. Magnetic resonance imaging and flexible hysterofiberscopic findings of a uterine adenofibroma: case report and literature review.;Watanabe;Case Rep Obstetr Gynecol,2018

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