Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report

Abstract

Rationale: Perianal abscess is a common disease of the anus and intestine. Surgery is an important treatment option for perianal abscess. However, some patients have a long healing time, poor healing effect after surgery, or even pseudo-healing. Platelet-rich plasma (PRP) is rich in platelets that can release a large number of factors when activated and promote wound healing. Moreover, there are few reports on the use of PRP for wounds that are difficult to heal after perianal abscess surgery. Patient concerns: The patient had reported a complaint of perianal swelling and discomfort associated with anal pain, which was considered a perianal abscess. Ceftriaxone, fumigation, and sitz bath were administered after mixed hemorrhoid and perianal abscess surgeries were performed; however, the wound remained unhealed for more than 3 months, and there was a fistula under the skin. Diagnosis: Perianal color ultrasonography revealed perianal abscess. Interventions: Autologous PRP treatment was performed 5 times for each patient. Outcomes: The postoperative wound healed within 15 days after 5 times PRP treatments. Lessons: PRP is a novel treatment option for pseudo-healing.