Relationship between stress and coronary artery disease: A comprehensive review

Author:

Elendu Chukwuka1ORCID,Amaechi Dependable C.2,Elendu Tochi C.3,Jingwa Klein A.4,Okoye Osinachi K.5,Fiemotonghan Border-ere6,Chirinos Grecia A.7,Agada Deborah8,John Okah Minichimso8,Adebayo Opeyemi D.8,Dang Kanishk9,Egbunu Emmanuel10,Alabi Omotayo S.11,Nasre Vaibhav S.4,Yadav Cyrus P.4,Badru Muhydeen D.12

Affiliation:

1. University of California, Santa Cruz, CA

2. Igbinedion University, Okada, Nigeria

3. Imo State University, Owerri, Nigeria

4. Kazan State Medical University, Kazan, Russia

5. Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria

6. Jackson State University, Jackson, MS

7. Lisandro Alvarado Centroccidental University, Barquisimeto, Venezuela

8. Babcock University, Ilishan-Remo, Nigeria

9. Nicolae Testemițanu State University of Medicine and Pharmacy, Chişinău, Republic of Moldova

10. Federal Medical Centre, Bida, Nigeria

11. Osun State University, Osogbo, Nigeria

12. Obafemi Awolowo University, Ile-Ife, Nigeria.

Abstract

Coronary artery disease (CAD) poses a substantial public health challenge. This review examines the intricate relationship between psychological stress and CAD, drawing from recent research spanning the last 5 to 10 years. The literature review is organized around critical themes. It includes an analysis of genetic loci in CAD susceptibility and underscores the role of green environments in reducing cardiovascular risk. A quantitative analysis presents numerical findings for clarity, while pathophysiological mechanisms are elucidated through informative figures and diagrams. The review engages with controversies and disparities in the literature, offering a balanced perspective. A tabular comparative analysis outlines the strengths and limitations of existing approaches, emphasizing conflicting findings, and environmental factors. The review concludes by distilling key takeaways for healthcare professionals and researchers. Practical implications are explored, and lessons learned from the research process are reflected upon. The conclusion also suggests avenues for further study in understanding stress’s impact on CAD.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference26 articles.

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