Affiliation:
1. Selcuk University, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology (Ph.D.)
2. NECMETTIN ERBAKAN UNIVERSITY, FACULTY OF VETERINARY MEDICINE, DEPARTMENT OF PRECLINICAL SCIENCES, DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY (VETERINARY MEDICINE)
Abstract
Imidocarb dipropionate is a carbanilide derivative antiprotozoan drug. The drug is approved for use in animals for the treatment of tick-borne transmitted babesiosis (piroplasmosis) and anaplasmosis. However, its effectiveness against some other microorganisms transmitted by ticks has also been investigated. Although cattle, horses, donkeys, mules, dogs and sheep are defined as target species, they can also be used in other domestic and wild animals. Although it is recommended to use the drug as a single dose, it can be applied 2-3 days later if necessary. The therapeutic index of the drug is narrow, and attention should be paid to the dosage regimen. In this review, it could be tried to give information about the use of imidocarb in animal species, its success in treatment and its side effects.
Publisher
Veterinary Pharmacology and Toxicology Association
Reference92 articles.
1. 1- Abdullah AS, Baggot JD, 1986. Influence of induced disease states on the disposition kinetics of imidocarb in goats. J Vet Pharmacol Ther, 9(2):192-197. https://doi.org/10.1111/j.1365-2885.1986.tb00029.x.
2. 2- Abdullah AS, Sheikh-Omar AR, Baggot JD, Zamri M, 1984. Adverse effects of imidocarb dipropionate (Imizol) in a dog. Vet Res Commun, 8: 55-59. https://doi.org/10.1007/BF02214695.
3. 3- Abutarbush SM, Alfaqeeh SM, Mustafa G, Qura'n L, Al-Majali AM, 2013. Evaluation of the use of atropine sulfate, a combination of butylscopolammonium bromide and metamizole sodium, and flunixin meglumine to ameliorate clinical adverse effects of imidocarb dipropionate in horses. Am J Vet Res, 74(11):1404-1408. https://doi.org/10.2460/ajvr.74.11.1404.
4. 4- Adam M, Pikalo J, Snyder A, Steinrigl A, Köller G, Schusser GF, 2017. Equine Piroplasmosis – a case of severe Babesia caballi infection associated with acute renal failure. Berl Munc Tierarztl Wochenschr,130, 111-118. https://doi.org/10.2376/0005-9366-16064.
5. 5- Adams LG, 1981. Clinicopathological aspects of imidocarb dipropionate toxicity in horses. Res Vet Sci, 31(1):54-61.