Analysis of recurrently protected genomic regions in cell-free DNA found in urine

Author:

Markus Havell1ORCID,Zhao Jun12ORCID,Contente-Cuomo Tania1ORCID,Stephens Michelle D.1ORCID,Raupach Elizabeth1ORCID,Odenheimer-Bergman Ahuva1,Connor Sydney1ORCID,McDonald Bradon R.1ORCID,Moore Bethine1,Hutchins Elizabeth1ORCID,McGilvrey Marissa1ORCID,de la Maza Michelina C.2ORCID,Van Keuren-Jensen Kendall1,Pirrotte Patrick1ORCID,Goel Ajay34ORCID,Becerra Carlos3,Von Hoff Daniel D.1ORCID,Celinski Scott A.35ORCID,Hingorani Pooja2,Murtaza Muhammed1ORCID

Affiliation:

1. Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

2. Phoenix Children’s Hospital, Phoenix, AZ 85016, USA.

3. Baylor Scott and White Research Institute, Baylor University Medical Center, Dallas, TX 75204, USA.

4. City of Hope, Duarte, CA 91010, USA.

5. Department of Surgery, Baylor University Medical Center, Dallas, TX 75214, USA.

Abstract

Fragmentation patterns of cell-free DNA from urine differ between healthy individuals and those with cancer.

Funder

National Cancer Institute

Science Foundation Arizona

Ben and Catherine Ivy Foundation

Arizona Women’s Board

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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