Neurophysiological signatures in Alzheimer’s disease are distinctly associated with TAU, amyloid-β accumulation, and cognitive decline-Reference-Cited by-同舟云学术

Neurophysiological signatures in Alzheimer’s disease are distinctly associated with TAU, amyloid-β accumulation, and cognitive decline

Published:2020-03-11 Issue:534 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ranasinghe Kamalini G.¹^ORCID,Cha Jungho¹^ORCID,Iaccarino Leonardo¹^ORCID,Hinkley Leighton B.²,Beagle Alexander J.¹,Pham Julie¹,Jagust William J.³^ORCID,Miller Bruce L.¹^ORCID,Rankin Katherine P.¹^ORCID,Rabinovici Gil D.¹²,Vossel Keith A.¹⁴^ORCID,Nagarajan Srikantan S.²

Affiliation:

1. Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.

2. Department Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94143, USA.

3. Helen Wills Neuroscience Institute, UC Berkeley, Berkeley, CA 94720, USA.

4. N. Bud Grossman Center for Memory Research and Care, Institute for Translational Neuroscience, and Department of Neurology, University of Minnesota, Minneapolis, MN 55455, USA.

Abstract

Alpha and delta-theta brain oscillation deficits depict diverse associations with amyloid and TAU accumulations and with cognitive decline in AD.

Funder

National Science Foundation

National Institutes of Health

National Institute on Aging

Larry L. Hillblom Foundation

Alzheimer’s Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine