A live vaccine rapidly protects against cholera in an infant rabbit model-Reference-Cited by-同舟云学术

A live vaccine rapidly protects against cholera in an infant rabbit model

Published:2018-06-13 Issue:445 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Hubbard Troy P.¹²^ORCID,Billings Gabriel¹²^ORCID,Dörr Tobias¹²^ORCID,Sit Brandon¹²^ORCID,Warr Alyson R.¹²^ORCID,Kuehl Carole J.¹²^ORCID,Kim Minsik¹²^ORCID,Delgado Fernanda²³^ORCID,Mekalanos John J.¹^ORCID,Lewnard Joseph A.⁴^ORCID,Waldor Matthew K.¹²³⁵^ORCID

Affiliation:

1. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

2. Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.

3. Howard Hughes Medical Institute, Boston, MA 02115, USA.

4. Center for Communicable Disease Dynamics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.

5. Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.

Abstract

An engineered cholera vaccine candidate mediates colonization resistance and disease protection within 1 day in an infant rabbit model.

Funder

Howard Hughes Medical Institute

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference42 articles.

1. Cholera in Yemen

2. Updated Global Burden of Cholera in Endemic Countries

3. Cholera

4. Feasibility and effectiveness of oral cholera vaccine in an urban endemic setting in Bangladesh: a cluster randomised open-label trial

5. Use of Vibrio cholerae Vaccine in an Outbreak in Guinea

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