HIV latency in isolated patient CD4 + T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing-Reference-Cited by-同舟云学术

HIV latency in isolated patient CD4 + T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing

Published:2018-02-28 Issue:430 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Yukl Steven A.¹^ORCID,Kaiser Philipp¹^ORCID,Kim Peggy¹^ORCID,Telwatte Sushama¹^ORCID,Joshi Sunil K.¹^ORCID,Vu Mai¹^ORCID,Lampiris Harry¹,Wong Joseph K.¹^ORCID

Affiliation:

1. San Francisco Veterans Affairs Medical Center and University of California, San Francisco, 4150 Clement Street, 111W, San Francisco, CA 94121, USA.

Abstract

HIV latency may not be governed by a lack of transcriptional initiation, but rather by blocks to RNA elongation, polyadenylation, and splicing.

Funder

National Institute of Allergy and Infectious Diseases

U.S. Department of Veterans Affairs

National Institute of Diabetes and Digestive and Kidney Diseases

amfAR, The Foundation for AIDS Research

Swiss National Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine