Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging

Author:

Stoffels Ingo123,Morscher Stefan45,Helfrich Iris123,Hillen Uwe123,Leyh Julia123,Burton Neal C.4,Sardella Thomas C. P.4,Claussen Jing4,Poeppel Thorsten D.6,Bachmann Hagen S.7,Roesch Alexander123,Griewank Klaus123,Schadendorf Dirk123,Gunzer Matthias8,Klode Joachim123

Affiliation:

1. Department of Dermatology, Venerology, and Allergology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.

2. West German Cancer Center, University of Duisburg-Essen, 45122 Essen, Germany.

3. German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

4. iThera Medical GmbH, 81379 München, Germany.

5. Institute for Biological and Medical Imaging, Technische Universität München, and Helmholtz Center Munich, 85764 München, Germany.

6. Department of Nuclear Medicine, University of Duisburg-Essen, 45122 Essen, Germany.

7. Institute of Pharmacogenetics, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.

8. Institute for Experimental Immunology and Imaging, Imaging Center Essen (IMCES), University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.

Abstract

Optoacoustic imaging strategies can be used to identify metastasis in excised lymph nodes and to determine SLN status in patients noninvasively.

Funder

Wilhelm Sander-Stiftung

European Union Seventh Framework Programme

German Federal Ministry of Education and Research (BMBF)

Mercator Research Center Ruhr

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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